In 1988, Irwin Rosenberg proposed that the term sarcopenia be used to describe the major changes in body composition and function associated with aging. In so doing, he intended primarily to draw the attention of the scientific community to loss of lean body mass (LBM). At the time, isolated LBM reduction was already regarded as the most striking phenomenon among the various functional and organic declines that accompany aging, affecting mobility, ambulation, nutritional status, nutrient and energy intake, independence, and even breathing.