Due to the major health problems caused by pollution in large urban centers, the use of meteorological models coupled with chemical models, resulting in quality prediction models, has increased significantly in recent years. Examples of this type of use are the WRF-CHEM models, used in several countries of the world, and SPM-BRAMS, recently developed by researchers from the University of São Paulo and INPE and operationally used in the MASTER laboratory at IAG-USP. Although the model is used to assess the concentrations of the main pollutants monitored in the region, comparisons are made between the concentrations of fine particulate matter (PM2.5) envisaged and those derived from observations in the CETESB network. The PM2. 5 is related to deleterious effects on health and the study of the establishment of a quality standard for air pollutants is being studied. In addition to the issue of the relationship with negative health impacts, there are also impacts to the climate, since the particulate matter is related to the formation of precipitation and extinction of the radiation.