Association between nutritional therapy and complications in patients diagnosed with COVID-19 followed in the state of Pernambuco
Revista Ciências em Saúde
Association between nutritional therapy and complications in patients diagnosed with COVID-19 followed in the state of Pernambuco
Autor Correspondente: Almeida KMM | [email protected]
Palavras-chave: Coronavirus infections, Nutrition, Nutrition therapy, SARS-CoV-2, Signs and symptoms
Resumos Cadastrados
Resumo Português:
Objetivo: Analisar a associação entre terapia nutricional e complicações em pacientes diagnosticados com COVID-19 acompanhados no estado de Pernambuco. Métodos: Estudo do tipo coorte prospectiva, realizado a partir da análise de dados secundários de pesquisa multicêntrica, de junho de 2020 a junho de 2021. Foram incluídos pacientes de ambos os sexos, maiores de 18 anos, hospitalizados por COVID-19 em enfermarias e/ou unidades de terapia intensiva de oito hospitais. Foram coletados dados sociodemográficos e econômicos, de estado nutricional, terapia nutricional, complicações gastrointestinais e desfecho clínico, durante a admissão e término do internamento. Resultados: A amostra foi composta por 272 pacientes, com uma idade mediana de 67 anos (IIQ 54 - 76), distribuindo-se de forma semelhante entre homens e mulheres (50,4% vs. 49,6%). Foi observada uma maior frequência de sobrepeso/obesidade (40,31%). Inapetência (12,88%) e disgeusia (8,28%) foram as alterações mais frequentes. Foi observado que 84,6% receberam dieta precoce, a adequação calórica variou entre 72,1% e 60,7%, a via oral entre 82,4% e 70,7%, a maioria (58%) recebeu até 1,3 g de proteína ao dia e 46,7% foram a óbito. A adequação calórica se associou a disgeusia (p = 0,040) e desfecho clínico (p = 0,044) e apresentou tendência de associação ao vômito (p = 0,077). Não se encontrou associação com as proteínas. Conclusão: A terapia nutricional está associada a sintomas gastrointestinais, como vômitos e disgeusia e ao desfecho clínico dos pacientes com COVID-19.
Resumo Inglês:
Objective: To analyze the association between nutritional therapy and complications in patients diagnosed with COVID-19 followed in Pernambuco. Methods: A prospective cohort study was conducted to investigate secondary data from multicenter research from June 2020 to June 2021. Patients of both sexes over 18 years old were hospitalized for COVID-19 in wards or intensive care units of eight hospitals. Sociodemographic and economic data, nutritional status, nutritional therapy, gastrointestinal complications, and clinical outcome were collected during admission and at the end of hospitalization. Results: The sample consisted of 272 patients, with a median age of 67 years (IQR 54 - 76), equally distributed between men and women (50.4% vs. 49.6%). A higher frequency of overweight/obesity (40.31%) was observed. The most frequent alterations were inappetence (12.88%) and dysgeusia (8.28%). It was observed that 84.6% received an early diet, the caloric adequacy varied between 72.1% and 60.7%, the oral route between 82.4% and 70.7%, the majority (58%) received up to 1.3 g of protein per day, and 46.7% died. Caloric adequacy was associated with dysgeusia (p = 0.040) and clinical outcome (p = 0.044) and tended to be associated with vomiting (p = 0.077). No association was found with proteins. Conclusion: Nutritional therapy is associated with gastrointestinal symptoms such as vomiting and dysgeusia and the clinical outcome of patients with COVID-19.
