Angiogenic factors and ovarian follicle development

Animal Reproduction

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ISSN: 19843143
Editor Chefe: [email protected]
Início Publicação: 31/07/2004
Periodicidade: Trimestral
Área de Estudo: Medicina Veterinária

Angiogenic factors and ovarian follicle development

Ano: 2009 | Volume: 6 | Número: 2
Autores: J.B. Bruno, M.H.T. Matos, R.N. Chaves, J.J.H. Celestino, M.V.A. Saraiva, I.B. Lima-Verde, V.R. Araújo, J.R. Figueiredo
Autor Correspondente: J B Bruno | [email protected]

Palavras-chave: angiogenesis, follicle, growth factors, ovary

Resumos Cadastrados

Resumo Inglês:

Ovarian follicles require an adequate blood
supply for oxygen, nutrients and hormones, in addition
to eliminating CO2 and other metabolites. Acquisition of
an adequate vascular supply is probably a limiting step
in the selection and maturation of the dominant follicle.
In this way, there is a progressive interest in the study of
the growth factors involved in the angiogenic process.
In addition, a better understanding about the
mechanisms that regulate the expression and action of
these factors could be a key point to increase the
reproductive performance in females. Therefore, this
review aims to summarize current data on the
importance of the pro- and anti-angiogenic growth
factors which regulate angiogenesis in ovarian follicle
development.