Synthesis of some new series of Mannich base derivatives and their antimicrobial activity

Ano: 2011 | Volume: 3 | Número: 1

Autores: Radha Krishnan Surendra Kumar, Akbar Idhayadhulla, Abdul Jamal Abdul Nasser

Palavras-chave: imidazole, mannich condensation, antibacterial, antifungal activity

Resumo Inglês:

A series of 1-[(4-substituted phenyl)(hydrazinyl)methyl]-1H-imidazole (1-6) were synthesized by Mannich reaction. Synthesized compounds 1-6 were confirmed by IR, 1H NMR, 13C NMR, Mass and elemental analysis. Synthesized compounds 1-6 were screened for antimicrobial activity.