Synthesis, characterization and antibacterial activity of new salicylhydrazide containing azopyrazoles

Orbital: The Electronic Journal of Chemistry

Endereço:
Av. Senador Filinto Muller, 1555
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79074-460
Site: http://www.orbital.ufms.br
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ISSN: 19846428
Editor Chefe: Adilson Beatriz
Início Publicação: 28/02/2009
Periodicidade: Trimestral
Área de Estudo: Química

Synthesis, characterization and antibacterial activity of new salicylhydrazide containing azopyrazoles

Ano: 2010 | Volume: 2 | Número: 3
Autores: Bhupendra P. Patel, Hasmukh S. Patel, Purvesh J. Shah
Autor Correspondente: Bhupendra P. Patel | [email protected]

Palavras-chave: pyrazoline-5-one, salicylhydrazide, antimicrobial activity, spectral studies

Resumos Cadastrados

Resumo Inglês:

Various ethyl-2-substituted phenyl hydrazono-3-oxobutyrate (2a-h)
condensation with 2-hydroxy benzoic acid hydrazide (3) to afford 1-(2-hydroxybenzoyl)-
3-methyl-4-(2- substituted phenyl hydrazono)-1H-pyrazol-5(4H)-one (4a-h). The
structures of all these compounds (4a-h) were recognized on basis of analytical and
spectral data. The newly synthesized compounds were evaluated for their antimicrobial
activity against various bacteria and fungi.