The post-mortem diagnosis of vasocclusive crisis in sickle cell disease
Autopsy And Case Reports
Endereço:
Av. Prof. Lineu Prestes, 2565
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05508-000
Site: http://www.autopsyandcasereports.org
Telefone: (11) 3091-9448
ISSN: 22361960
Editor Chefe: Maria Claudia Nogueira Zerbini
Início Publicação: 28/02/2011
Periodicidade: Trimestral
Área de Estudo: Medicina
The post-mortem diagnosis of vasocclusive crisis in sickle cell disease
Ano: 2014 | Volume: 4 | Número: 3
Autores: V. Bhatia, R. Juneja, V. Juvekar
Autor Correspondente: V. Bhatia | [email protected]
Autor Correspondente: V. Bhatia | [email protected]
Resumos Cadastrados
Resumo Inglês:
Sickle cell disease (SCD) comprises a group of genetic blood disorders that affect the hemoglobin
molecular structure, and in some cases, the association with hemoglobin synthesis. In sickle cell anemia, the replacement of glutamic acid by valine at the 6th position on the beta chain from the N terminal results in the synthesis of the abnormal hemoglobin, called hemoglobin S(HbS).